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Medical profile of sedentary women with and without metabolic syndrome (MS)
Author(s) -
Jitomir Jean,
Chandran R,
Shelmadine B,
Beavers K,
Kerksick C,
Wilborn C,
Wismann J,
Nassar E,
Dove J,
Galbreath M,
Harvey T,
La Bounty P,
Campbell B,
Ferreira M,
Cooke M,
Iosia M,
Rasmussen C,
Bowden R,
Wilson R,
Kreider R
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.2_supplement.788
Subject(s) - medicine , waist , endocrinology , zoology , obesity , biology
543 sedentary women (44±11 yrs, 92±17 kg; 45±4% body fat) were medically screened prior to participation in an exercise and weight loss program. Subjects were divided into those with less than (n=281) or more than (n=262) three criteria for MS. Medical data and fasting blood samples were collected and analyzed by one‐way ANOVA for the non‐MS and MS groups, respectively. Women with MS had significantly higher (p<0.001) age (42.8±11 vs 46.3±10 yrs), weight (88.1±16 vs 96.5±17 kg), BMI (33.0±6 vs 36.0±6), waist circumference (95±12 vs 103±12 cm), hip circumference (118±13 vs 124±13 cm), DEXA percent body fat (44.6±5 vs 45.8±4 %), resting HR (69.6±10 vs 72.0±10 bpm), resting SBP (121±12 vs 131±16 mmHg), resting DBP (79±8 vs 85±9 mmHg), triglycerides (103±44 vs 171±87 mg/dl), total cholesterol (198±37 vs 211±46 mg/dl), LDL (115±31 vs 128±35 mg/dl), CHL/HDL ratio (3.5±0.8 vs 4.6±1.1), glucose (92±11 vs 106±26 mg/dl), and REE(1,606±243 vs 1,755±276 kcals/d). HDL (58±14 vs 48±13 mg/dl) and maximal oxygen uptake (21.5±5 vs 19.7±4 ml/kg/min) values were significantly lower in women with MS. These findings indicate that a high percentage of sedentary women interested in entering a fitness and weight loss program have MS. Additionally, women with MS have medical profiles that place them at higher risk for chronic and/or metabolic disease.