Premium
The blood levels of hs‐CRP, leptin and adiponectin are significantly different among the normal weight, overweight and obese Korea women
Author(s) -
Shin Gina,
Lee In seok,
Choue Ryowon
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.2_supplement.766
Subject(s) - leptin , adiponectin , overweight , medicine , obesity , endocrinology , anthropometry , body mass index , normal weight , adipokine , insulin resistance
The purpose of this study was to investigate the difference of hs‐CRP, leptin and adiponection levels as significant prognostic indicators of the obesity‐related chronic diseases in normal weight, overweight and obese women. Hundred ten women were assigned into three groups, normal weight (BMI < 23 kg/m 2 ), overweight (BMI 23–25 kg/m 2 ) and obese (BMI > 25 kg/m 2 ). Anthropometric assessment was carried and blood levels of hs‐CRP, leptin and adiponectin were measured. Blood levels of hs‐CRP were significantly higher in obese group compared with normal and overweight groups( 0.046 ± 0.076 vs. 0.078 ± 0.094 vs. 0.206 ± 0.153 mg/dL). Leptin levels of normal weight group were significantly lower than those of overweight and obese groups( 4.7 ± 2.4 vs. 10.7 ± 4.5 vs. 13.3 ± 4.6 ng/mL). Adiponectin levels were significantly higher in normal weight group (10517.0 ± 4255.7 vs. 8071.0 ± 2828.2 vs. 6448.0 ± 2449.8 ng/mL). The levels of hs‐CRP and leptin were positively correlated to body fat mass however, adiponection levels were negatively correlated (p < 0.05). Inverse correlations were observed between hs‐CRP and adiponection as well as leptin and adiponection (p < 0.05). The results suggest that the blood levels of hs‐CRP, leptin and adiponectin could be used as significant prognostic indicators for obesity‐related condition.