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Growth abnormalities and hypertension status in a pediatric HIV+ population
Author(s) -
Balakrishnan Asha,
Borum Peggy R.
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.2_supplement.747
Subject(s) - percentile , medicine , linear growth , blood pressure , population , human immunodeficiency virus (hiv) , linear correlation , pediatrics , immunology , environmental health , statistics , mathematics
Linear growth delay and high blood pressure are health issues in pediatric HIV+ patients. To evaluate trends in linear growth (Ht) and blood pressure (BP), a cross‐sectional analysis was conducted in HIV+ pediatric patients from Shands Children's Hospital for each year during 1999–2007; a patient seen continually for 9 years would contribute 9 points for the data set. Linear growth (n=598 data points) and hypertension status (n=434) are reported in the tables below. The percent of patients with an average height below the 5th percentile increased in 2005–2007, indicating a concerning trend of declining linear growth in this population. The percent of patients with normal BP increased in 2005–2007, suggesting an improvement in hypertension status. More patients (30%) with a CD4<25% have height between the 5th and 15th percentiles, compared to patients (16%) with a CD4>25% (p=0.008). Thus, an impaired immune status appears to adversely impact linear growth. A similar analysis done for BP revealed no significant correlation between CD4% and hypertension status.