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Mechanism and efficacy of diacylglycerol on energy expenditure and body composition in overweight women
Author(s) -
Yuan Quangeng,
Jones Peter
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.2_supplement.738
Subject(s) - overweight , crossover study , zoology , chemistry , triglyceride , lipogenesis , endocrinology , obesity , medicine , adipose tissue , biology , cholesterol , alternative medicine , pathology , placebo
Diacylglycerol (DAG) has the potential to control body weight by inducing energy expenditure (EE) and modifying body fat accumulation. Our objective was to examine the efficacy of DAG oil (Enova oil™) in comparison with control oil composed of sunflower oil, safflower oil and rapeseed oil in overweight women. Twenty‐six subjects consumed two treatment diets for 28 days separated by a 4‐week washout period according to a randomized crossover design. Twenty grams of either DAG or control oil were consumed in the morning under supervision with an additional 20 grams of either oil provided for lunch and/or supper. DAG oil failed to induce (p>0.05, n=24) total energy expenditure or (p>0.05, n=24) fat oxidation compared with the control. DAG did not alter the lean (p>0.05, n=19) mass, at trunk (p>0.05, n=19), android (p>0.05, n=26) and gynoid (p>0.05, n=26) areas, but did reduce the accumulation of total body fat (p<0.05, n=19), at trunk (p<0.05, n=19), android (p<0.05, n=26), and gynoid (p<0.05, n=26) areas. We conclude that DAG oil does not increase total EE or EE from fat and lean mass, but effectively increases post meal EE from CHO, and reduces fat accumulation in overweight female individuals. Supported by Heart and Stroke Foundation of Canada.