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Effect of diacylglycerol (Enova oil™) consumption on serum lipid profiles in overweight hypertriglyceridemic women
Author(s) -
Ramprasath Vanu Ramkumar,
Yuan Quangeng,
Jones Peter
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.2_supplement.737
Subject(s) - overweight , diacylglycerol kinase , sunflower oil , crossover study , blood lipids , triglyceride , morning , zoology , chemistry , cholesterol , medicine , obesity , endocrinology , food science , biology , biochemistry , enzyme , protein kinase c , alternative medicine , pathology , placebo
Diacylglycerol (DAG) oil, a potential weight‐control agent, may also lower serum lipids and reduce the risk of cardiovascular disease. Our objective was to investigate the effects of DAG (Enova oil™) on serum lipid levels in overweight hypertriglyceridemic women compared with control oil, composed of sunflower, safflower and rapeseed oils. Using a randomized crossover design, 26 subjects consumed two treatment diets, each lasting 28 days and separated by 4‐week washout periods. Twenty grams of either DAG or control oil were consumed in the morning under supervision with an additional 20 grams of either oil provided for lunch and/or supper. No significant changes were observed in the serum lipid levels between the two treatments. Total cholesterol was not affected (p=0.4619) by DAG treatment (5.11±0.90mmol/L) compared to control group (5.04±0.92mmol/L). TG showed a non‐significant (p=0.4928) change between DAG group (1.664±0.69mmol/L) and control (1.59±0.66mmol/L). HDL was not altered (p=0.6252) by DAG consumption (1.32±0.34mmol/L, DAG vs 1.31±0.30mmol/L, control), nor were LDL levels affected (p=0.6388) by DAG consumption (3.45±0.78mmol/L) compared with control (3.41±0.84mmol/L). Results suggest that consumption of DAG oil has no significant effect on serum lipids when compared with conventional oils. Supported by Heart and Stroke Foundation of Canada.