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Effects of Korean antioxidant plant extracts on immune activation
Author(s) -
Cho SooMuk,
Lee HaeYoun,
Yoo SunMi,
Park HongJu,
Yeum KyungJin,
Park KiMoon,
Chun HyeKyung
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.2_supplement.732
Subject(s) - antioxidant , chemistry , nitric oxide , glycine , immune system , polyphenol , biochemistry , in vivo , traditional medicine , food science , biology , amino acid , microbiology and biotechnology , immunology , medicine , organic chemistry
Recently, much attention has been focused on plant rich in antioxidants, because of their functions reducing oxidative damage and preserving biological functions of cells. In this experiment, the effects of Korean plant extracts containing antioxidant nutrient such as carotenoids and polyphenols on the activation of immune function had been studied. Angelica keiskei (green leafy vegetable) and Glycine max (black soybean) have been used as functional antioxidant plants as well as dietary source in Asian countries. The immune activation of the water and 40% ethanol extracts of Angelica keiskei and Glycine max had been studied. Different concentrations of plants extracts were used for nitric oxide and cytokine secretion of RAW 264.7 cells (mouse marcrophage) in in vitro experiments. Water extracts of Angelica keiskei and Glycine max increased the induction of IL‐6, TNF and nitric oxide in RAW 264.7 cells. These results suggest that Angelica keiskei and Glycine max be possible functional foods controlling in vivo homeostasis. (Supported by BioGreen 21 Program (code #20070301034009), RDA, Korea)