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Sex Differences in Resting Hemodynamics and Vascular Distensibility Following Resistance Exercise Training in Hypertensive Individuals
Author(s) -
Collier Scott Robert,
Frechette Vincent,
Sandberg Kathryn,
Smulyan Harold,
Tobin Melissa Marie,
Fernhall Bo
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.1_supplement.957.27
Subject(s) - arterial stiffness , medicine , pulse wave velocity , hemodynamics , cardiology , blood pressure , vascular resistance , diastole , aerobic exercise , resistance training , pulse pressure , endocrinology
Hypertension is associated with increased arterial stiffness, which leads to ventricular remodeling and increased risk for cardiovascular disease. While exercise can reduce blood pressure (BP) and attenuate the risk of hypertension, few studies have compared the hemodynamic and vascular effects of exercise in both men (M) and women (W). Moreover, while the BP‐lowering effects of aerobic exercise (AE) are well known, the antihypertensive effects of resistance exercise (RE) training (T) are less understood. We studied the effects of 4 weeks of AE and RE on resting hemodynamics (systolic and diastolic BP (SBP & DBP)), and arterial distensibility (pulse wave velocity (PWV)), in 34 pre‐to stage‐1 age‐matched essential hypertensives (21M and 13W, 48.2±7.0 yrs). Both AE and RE significantly decreased SBP (mm Hg) [(pre vs post T): M‐AE, 136±3.5 vs 131±2.9 & M‐RE, 132±2.9 vs 128±2.4; F‐AE, 147±5.5 vs 143±6.4 & F‐RE, 148±7.3 vs 142±8.5] and DBP (mm Hg) [(pre vs post T): M‐AE, 80±1.9 vs 76±1.9 & M‐RE, 78±2 vs 76±1.6; F‐AE, 81±2.5 vs 78±2.6 & F‐RE, 78±3.2 vs 68±3.4] in both sexes. In contrast, RE significantly increased PWV (m/s) in men [(pre vs post T): 11.4±0.86 vs 13.3±0.95] but had no effect in women [(pre vs post T): 10±1.6 vs 10.9±1.7]. These data suggest that both sexes would benefit from the BP‐lowering effects of RE but that hypertensive women have the added advantage compared to men, that RE does not increase arterial stiffness.