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Associations of maternal folate intake with antepartum and postpartum serum folate levels
Author(s) -
Kim Hyesook,
Lee Ah Young,
Chang Namsoo
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.1_supplement.888.2
Subject(s) - medicine , pregnancy , gestation , christian ministry , obstetrics , physiology , biology , philosophy , theology , genetics
This study was carried out to evaluate the effect of maternal folate intake on the maternal serum folate level. Pregnant women of 18–20 weeks of gestation were recruited from prenatal clinic in Seoul, Cheonan and Ulsan. In 429 pregnant women, dietary intake during pregnancy was assessed by a 24‐hour recall method. Serum folate level was analyzed by the radioimmunoassay(RIA). The daily mean energy and protein intakes were 1804.9 kcal (90.9% of EER), 68.1g (125.8% of EAR, 97.0% of RI), respectively. The average daily folate intake was 238.2 μg DFE (45.95% of EAR, 39.82% of RI) for the pregnant women. The maternal antepartum(18–20 wk) and postpartum(at delivery) serum folate concentration were 10.4 ± 7.9 ng/ml, 13.5 ± 9.3 ng/ml. The maternal antepartum serum folate level was significantly lower than that of the postpartum serum(p<0.001). Pregnant women whose intake of folate was above the median value showed a greater increase in postpartum serum folate level than those with intakes below the median(p<0.05). Maternal intake of folate was positively correlated with postpartum serum folate level (p<0.05). These results suggest that the maternal folate intake may affect the postpartum folate level. This work was supported by the Ministry of Environment and the Brain Korea 21 project in 2007