Premium
Vitamin D status is unaltered by mild weight reduction in obese premenopausal women
Author(s) -
Peterson Catherine Ann,
Ring Susan,
Loethen Joanne,
Rector R. Scott,
Thomas Tom R.,
Hinton Pamela S.
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.1_supplement.884.2
Subject(s) - weight loss , overweight , medicine , endocrinology , vitamin d and neurology , obesity , vitamin
Excess adiposity negatively affects vitamin D status because of its deposition in fat compartments. Limited data are available characterizing weight loss effects on vitamin D status. We hypothesize that body fat loss is associated with increased serum 25‐hydroxyvitamin D (25OHD) concentrations in obese premenopausal women after weight loss. Since increased physical activity is linked with higher serum 25OHD, we also explored the effects of exercise mode on vitamin D status. 37 overweight to class I obese sedentary, non‐smoking women (18–35 y) were randomized to one of three treatments designed to achieve a 5% reduction in body weight in 6 wk: energy restriction (DIET, n=11), energy restriction + non‐weight bearing aerobic exercise (CYCLE, n=13), or energy restriction + weight‐bearing aerobic exercise (RUN, n=13). Body composition was assessed by 3‐site skinfold measurement and 25OHD serum concentrations were measured by RIA before and after weight loss. While weight loss was similar among groups, the RUN group lost more body fat than the other groups (p<0.001). There was no effect of total weight or fat loss, regardless of method, on serum 25OHD concentrations. In conclusion, mild reductions in body weight and percent fat by energy restriction alone or with exercise did not alter vitamin D status in obese premenopausal women. Support: Dept. of Nutr. Sciences Margaret Mangel Research Catalyst & UM Research Council.