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The effects of dietary protein on serum IGF‐1 levels in adult humans
Author(s) -
Donnelly Kevin,
Beare Tianna,
Clapper Joan,
Specker Bonny
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.1_supplement.883.8
Subject(s) - weaning , medicine , dietary protein , food frequency questionnaire , endocrinology , longitudinal study , serum concentration , physiology , pathology
Positive associations have been observed between serum IGF‐1 and dietary protein. IGF‐1 concentrations appear to be influenced by protein source in pre‐pubertal boys, and middle aged and elderly men. Our hypothesis was that IGF‐1 concentrations would be associated with total protein intake, and not be associated with the protein source. Data were obtained from 115 participants (58 females) aged 20–66 years in the South Dakota Rural Bone Health Study (SDRBH), a longitudinal study of lifestyle on bone density. Fasting blood samples were collected from subjects who completed a protein food frequency questionnaire (FFQ) and at least 3 24‐hour quarterly dietary recalls within a 1‐year period. Pregnant, weaning, and lactating women were excluded. Contrary to our hypothesis there was no association between fasting serum IGF‐1 concentrations and total protein intake. However, fasting serum IGF‐1 concentrations were different in males between low and high poultry protein consumers (115 ± 27 vs. 143 ± 48 ng/mL, p=0.006, respectively). Supported by NIH AR47852.