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The effect of resistance training on systemic inflammatory markers in middle‐aged and older adults
Author(s) -
Barnes Jill Nicole,
CortezCooper Miriam Y.,
Anton Maria M.,
Tanaka Hirofumi
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.1_supplement.753.34
Subject(s) - medicine , systemic inflammation , resistance training , inflammation , middle age , insulin resistance , pathophysiology , aerobic exercise , natriuretic peptide , strength training , physical therapy , endocrinology , obesity , heart failure
Systemic inflammation has been implicated in the pathophysiology of cardiovascular disease. There is accumulating evidence that aerobic exercise has a beneficial effect on inflammatory markers. However, it is unclear whether the same is true for resistance exercise. Resistance training is increasingly prescribed for middle‐aged and older adults to improve overall health. Currently, it is not known whether the recommended amount of resistance training is sufficient to reduce systemic inflammation in middle‐aged and older adults. Plasma samples of 27 sedentary but healthy middle‐aged and older adults (aged 54±8 yr) who had undergone 13 weeks of supervised resistance training (10 exercises at ∼70% of 1RM, 3 d/wk) or supervised stretching (attention and time control) were analyzed in this retrospective analysis. The resistance training group increased lean body mass (p<0.01) and maximum strength of the major muscle groups (p<0.05). After 13‐weeks, blood pressure and fasting glucose, cholesterol, and triglycerides did not change. Concentrations of C‐reactive protein, C‐type natriuretic peptide, and tumor necrosis factor‐α were unaltered by either intervention. Our results indicate that the amount of resistance training currently recommended is not sufficient to reduce systemic inflammatory markers in healthy middle‐aged and older adults. Supported by NIH awards AG20966, HL072729