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High Fruit and Vegetable Intakes are Associated with Lower Homocysteine Levels in Cuban‐Americans
Author(s) -
Zarini Gustavo,
Gomez Gianna Perez,
Nath Subrata,
Huffman Fatma G
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.1_supplement.702.28
Subject(s) - quartile , medicine , confounding , vitamin b12 , homocysteine , diabetes mellitus , logistic regression , environmental health , zoology , endocrinology , biology , confidence interval
We examined the relationship between fruit and vegetable intake with homocysteine (HCY) levels in Cuban‐Americans with (n=182) and without (n=166) type 2 diabetes mellitus (T2DM). Subjects were randomly recruited from Miami‐Dade and Broward Counties, Florida. HCY levels were analyzed from fasting blood. Dietary intakes were determined using FFQ. Reported fruit and vegetable intakes were summed to obtain a single variable. Subjects were divided into quartiles for total fruit and vegetable intake. Statistical analyses used SPSS and included descriptive statistics, multinomial logistic regression and ANCOVA, controlling for age, gender, T2DM status, hypertension status, BMI, smoking, alcohol, total energy, folate and vitamin B12 intakes, vitamin supplement use (multivitamins, folate and vitamin B12). Mean fruit and vegetable intake differed significantly (all p‐values<.001) across quartiles, with values of 7.0, 10.5, 13.2, and 15.4, respectively. T2DM subjects were more likely than non‐diabetics to be in the lower and median quartiles of fruit and vegetable intake, p<.05. After adjustment for potential confounders, subjects in the 2nd quartile had significantly higher HCY levels than subjects in the 4th quartile, p=.034. However, post hoc analyses revealed that this was true only for non‐diabetics. Higher intakes of fruits and vegetables in Cuban‐Americans are associated with lower HCY levels.