Premium
Dietary true digestible calcium to phosphorus ratio affects phosphorus utilization and renal sodium and phosphate co‐transporter gene expressions in post‐weaned pigs
Author(s) -
Wang Zirong,
Archbold Tania,
Yang Chengbo,
Fan Ming Z
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.1_supplement.691.5
Subject(s) - weanling , phosphorus , zoology , feces , chemistry , sodium , randomized block design , calcium , medicine , phosphate , endocrinology , excretion , biology , biochemistry , agronomy , ecology , organic chemistry
This study was conducted with 36 Yorkshire weanling barrows of average initial and final BW of 11.5 and 17.7 kg and the pigs were fed six diets for six blocks according to a completely randomized block design. The six diets were corn and SBM‐based and contained six true fecal digestible Ca to true fecal digestible P ratios (diet 1, 0.56:1; diet 2, 0.68:1; diet 3, 0.96:1; diet 4, 1.35:1, diet 5, 1.46:1, and diet 6, 1.94:1) formulated by supplementing gradient levels of limestone. Each experimental period consisted of 15 d with 10‐day adaptation and 4‐day collection of representative fecal and urinary samples as well as total volumes of urinary excretions. Changes in the dietary Ca to P ratio had quadratic effects ( P = 0.02) on average daily feed intake and average daily gain with optimal responses occurred in diets 3 and 4. Increases in the dietary Ca to P ratio had quadratic effects ( P < 0.05) on the efficiency of digestive and post‐absorptive utilization of dietary P with optimal responses observed for diets 3 and 4. Renal sodium‐phosphate co‐transporter gene IIa (NaPi‐IIa) and III (NaPi‐III) mRNA expressions were linearly affected ( P < 0.05), while the jejunal NaPi‐IIc and NaPi‐III mRNA abundances were not affected ( P > 0.05) by changes in the dietary Ca to P ratio. In conclusion, changes in the dietary Ca to P ratio have significant effects on growth performance, and efficiency of P utilization. Dietary true digestible Ca to true digestible P ratio of 0.96:1 to 1.35:1 should be used to guide the formulation of diets for the post‐weaned pig. Supported by OMAFRA and NSERC.