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In vivo subcutaneous injection of Alcian blue at acupuncture points to trace a circulatory path from skin to organs
Author(s) -
Han HyunJung,
Sung Baeckkyoung,
Ogay Vyacheslav,
Soh KwangSup
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.1_supplement.1198.6
Subject(s) - acupuncture , dorsum , kidney , medicine , circulatory system , subcutaneous injection , anatomy , acupuncture point , subcutaneous tissue , pathology , chemistry , alternative medicine
Acupuncture has been thought to be a therapeutic treatment to regulate the function of internal organs by stimulating singular points at skin. This study was designed to trace a path from acupoints to corresponding organs by subcutaneous injection of Alcian blue (Ab) at certain acupoints. As the injection points, two acupoints BL23 and GB25 in rats, the control points of kidney, were selected and 200 μℓ of Ab was injected. After 2–7 hours from administration, internal organs were observed with a stereomicroscope. Ab‐stained corpuscles (Bong‐Han corpuscles) and spots along flow paths were observed from the injection points toward cranial direction in the dorsal skin. Furthermore, Ab‐stained spots were detected in the outer medulla region of the kidney, which showed that the Ab flowed from BL23 and GB25 in skin to kidney. In conclusion, the Ab injection at acupoints demonstrated a circulatory path from specific acupuncture points in skin to their corresponding internal organs. This can be utilized as a new effective drug delivery path.