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CHEMICAL MICRO‐SENSORS FOR BIOMEDICAL RESEARCH
Author(s) -
TAHA ZIAD HUSSEIN
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.1_supplement.1154.8
Subject(s) - hydrogen sulfide , carbon monoxide , nanotechnology , linearity , materials science , hydrogen sulfide sensor , chemistry , biological system , organic chemistry , electronic engineering , sulfur , engineering , biology , catalysis
The design, performance and applications of chemical micro‐sensors for biomedical research are described. Nitric oxide (NO) sensors have been built to enable the users to measure NO in a wide range of biological and non‐biological samples. The sensors incorporate the sensing elements behind a gas permeable membrane to assure the selectivity of measurements in addition to isolating these elements from any ionic changes in the sample resulting in a stable measurements. Many sensors were built to fit many applications. The sensors are capable of measuring NO at the nanomolar levels with fast response time and wide linearity. The sensors have been used to measure NO in live animals, brain slices, cell culture, tissue samples, and many others. The sensors can indirectly measure nitrite at the nano‐molar level. A hydrogen sulfide sensor was designed to selectively detect hydrogen sulfide in biological samples. Sensors with tip diamater size of 200–500 micron were prepared. Other sensors include pH, oxygen and carbon monoxide were designed.