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Oat reduces serum total cholesterol in healthy adult dogs
Author(s) -
Yu Shiguang
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.1_supplement.1117.1
Subject(s) - basal (medicine) , cholesterol , medicine , zoology , diabetes mellitus , endocrinology , biology
Hypercholesterolemia occurs in various diseases in dogs, such as chronic kidney disease, hypothyroidism, diabetes mellitus, cholestasis, hyperadrenocorticoidism, idiopathic hypercholesterolemia, and lipoproteinlipase deficiency. The objective of this study is to investigate whether dietary oat reduces serum cholesterol in dogs. Forty‐eight healthy adult beagles were fed a basal dry dog food for 4 weeks. The basal food is nutritionally complete and balanced for an adult dog. Afterwards, dogs were randomly divided into 4 groups (week 0 of the study), 12 dogs per group. Each group was given either the basal food (control), basal food with 5%, 10%, or 20% of oat groat for additional 8 weeks. Oat groat was added to the basal food at the expense of rice and corn so that proximate analysis was similar among the foods. Serum total cholesterol was measured in weeks 0 and 8 of the study. Comparing to week 0, serum total cholesterol change was 1%, 2.1%, −5.6%, and −14.7% after dogs were fed the food containing 0%, 5%, 10%, or 20% of oat groat for 8 weeks, respectively. There was a significant difference in serum total cholesterol change between the control food and the food containing 20% oat groat (p < 0.05). Food intake was similar among dietary groups. Body weight was not affected by dietary oat groat during the study. The results of this study show that dietary oat at 20% may be beneficial to dogs with hypercholesterolemia.