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Bay leaves improve glucose and lipid profile of people with type 2 diabetes mellitus
Author(s) -
Khan Alam,
Zaman Goher,
Anderson Richard A.
Publication year - 2007
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.21.6.lb46-d
Subject(s) - bay , cholesterol , diabetes mellitus , placebo , medicine , type 2 diabetes , type 2 diabetes mellitus , endocrinology , zoology , chemistry , biology , geography , alternative medicine , archaeology , pathology
Bay leaves ( Laurus nobilis ) have been shown to improve insulin function in vitro but the effects on people have not been determined. The objective of this study was to determine if bay leaves may be important in the prevention and/or alleviation of type 2 diabetes mellitus (DM). Forty people, with type 2 DM were divided into 4 groups & given capsules containing 1, 2 or 3 g of ground bay leaves per day or placebo followed by 10 day washout period. All three levels of bay leaves reduced serum glucose with significant decreases ranging from 21 to 26% after 30 d. Triglycerides also decreased with decreases of 4 to 33% after 30 d and total cholesterol decreased, 20 to 24%, after 30 d with larger decreases in LDL cholesterol of 32 to 40%. HDL cholesterol increased from 6 to 29%. The reduction in cholesterol and LDL were significant in all three groups while TGL and HDL were significantly changed only in groups in 1 and 2. There were no significant changes in the placebo group. In summary, consumption of 1–3 g of bay leaves/d for 30 d decreased risk factors for diabetes including glucose and lipids and suggests that bay leaves are beneficial for people with type 2 DM. HEC, Pakistan financially supported this project.