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DTI‐based fiber tracking reveals a heterogeneous alteration of pennation angle upon muscle lengthening
Author(s) -
Heemskerk Anneriet M.,
Sinha Tuhin K,
Ding Zhaohua,
Damon Bruce M.
Publication year - 2007
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.21.6.lb118-c
Subject(s) - muscle fibre , fiber , anatomy , tracking (education) , biomedical engineering , chemistry , medicine , psychology , skeletal muscle , pedagogy , organic chemistry
Introduction Diffusion tensor MRI (DTI)‐based fiber tracking can determine the 3D structure of muscle, including pennation angle (). The goal of this study was to determine how changes upon muscle lengthening. Methods DTI and anatomical MR images were acquired of the tibialis anterior (TA) with the foot in 0° of plantarflexion (anatomical position), +15° of plantarflexion, and at 0° on a different day ( n =4). Fiber tracking was performed by following the direction of greatest diffusion from 28,000 starting points along each of the deep and superficial aspects of the TA’s aponeurosis. was measured as the orientation of the fiber tract with respect to the plane tangent to the starting point. Results Reproducibility: did not differ when the 0° measurement was repeated. Deep compartment: at the 0° foot position, increased from 19±4° (proximal portion) to 37±6° (distal portion). When the foot was rotated to +15°, decreased to 18±4° (proximal portion) and increased to 40±6° (distal portion). Superficial compartment: at 0°, increased from 19±4° (proximal portion) to 30±3° (distal portion). When the foot was rotated to +15°, decreased to 18±4° (proximal portion) and did not change in the distal portion. Conclusion Muscle lengthening causes heterogeneous changes in along the aponeurosis. This may relate to the non‐uniform material properties of the aponeurosis. Support NIH R01 AR050101 , R01 NS034834 , M01 RR00095