Premium
Canine Protein Requirement and Circulating Glucose Concentration During Weight Loss.
Author(s) -
Jewell Dennis Edward,
Toll Philip W.
Publication year - 2007
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.21.6.a743-a
Subject(s) - weight loss , lean body mass , body weight , endocrinology , resting energy expenditure , medicine , chemistry , composition (language) , venous blood , zoology , obesity , biology , linguistics , philosophy
Eighteen obese dogs, randomly assigned to three dietary protein level foods, were the subjects of this study to determine the effect of weight loss, at different protein levels, on change in body composition and responsiveness to oral glucose. The experimental protocol was reviewed and approved by the Institutional Animal Care and Use Committee. Responsiveness to glucose was determined through measurement of venous glucose while body composition was determined via dual energy x‐ray absorptiometry (DXA). Glucose concentration and DXA were measured before and after weight loss. All foods had identical energy content (2.7 kcal/g), but contained 18.2%, 23.1% and 27.1% protein. The study subjects were provided with food that supplied the resting energy requirement (RER, 70 X wt in kg 3/4 ) while they lost weight. All dogs effectively lost weight resulting in reduced blood glucose (P<0.05, both resting and after an oral glucose challenge). Maximal body protein was maintained during weight loss when the daily ration of food supplied more than 2.4g of protein/kg lean body mass.