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Are pre‐diabetes mellitus(pre‐DM) differ from diabetes mellitus(DM) patients?
Author(s) -
Lyu Jieun,
Lee Yunjung,
Ahn Chulwoo,
Park Jongsuk,
Kim Whayoung
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.21.6.a1055-c
Diabetes is recognized as a serious health problem and is dramatically increasing in Korea. The purpose of this study is to compare pre‐DM with DM patients in the anthropometry, hematological variables, and dietary intakes. The subjects were recruited from a diabetes clinic in Seoul and classified into pre‐DM(FBS<126mg/dl) and DM groups(FBS≥126mg/dl) based on fasting blood sugar. DM patients showed significantly higher weight and serum triglycerides concentration than pre‐DM. Intakes of energy, protein and fat were significantly higher in DM than in pre‐DM. But, serum concentrations of total cholesterol, HDL‐cholesterol and LDL‐cholesterol were not different between two groups. Since obesity is a serious problem in DM patients, subjects in each group were sub‐divided into OB(obese, BMI≥25kg/m 2 ) and NOB(non‐obese, BMI<25kg/m 2 ) according to BMI. No significant differences were found in waist‐hip ratio, %body fat and serum concentrations of triglycerides, total cholesterol, and HDL‐cholesterol between OB DM and OB pre‐DM. In conclusion DM showed higher weight and serum triglycerides concentration than pre‐DM, however, effects of obesity on anthropometry, hematological variables were not differ in DM and pre DM groups. (This work was supported by the second stage of BK21 Project in 2006 and by Seoul R&BD Program, N0. 10526)