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Effect of carnitine (CARN) supplementation in the total parenteral nutrition (TPN) of premature neonates: blood compartmentalization, growth and feeding
Author(s) -
Kanani Sainel,
Borum Peggy
Publication year - 2007
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.21.5.a715-c
Subject(s) - parenteral nutrition , calorie , enteral administration , carnitine , medicine , head circumference , endocrinology , biology , gestational age , pregnancy , genetics
Carnitine (CARN) is considered a conditionally essential nutrient for the premature neonate. The aim of this study was to evaluate the effects of CARN supplementation on blood CARN status, growth parameters and feeding characteristics. Seventy‐four premature neonates were given TPN with or without CARN supplementation of 10mg/kg/day. Plasma and red blood cell (RBC) total CARN concentrations were collected on Day 1 and Day 28. Enteral start and wean times (day of life when neonate received ≥50% total non‐protein calories from enteral sources), body weight, head circumference, and length were also assessed. Table 1: CARN, Growth and Feeding Parameters Plasma CARN was significantly increased in the CARN group but there was no difference in RBC CARN, suggesting different compartments. Overall, there was no difference between the control and CARN groups with respect to growth parameters and feeding characteristics. 1 CARN, Growth and Feeding Parameters