Premium
The effects of life styles and LifePak on human skin carotenoids scores measured by resonance Raman spectroscopy BioPhotonic Scanner
Author(s) -
Bi Senxu,
Li Changling,
Guo Hongwei,
Poole Stephen,
Zhu JiaShi
Publication year - 2007
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.21.5.a709
Subject(s) - carotenoid , sunlight , antioxidant , human skin , food science , chemistry , medicine , zoology , biology , biochemistry , physics , astronomy , genetics
This study was to assess the effects of life styles and dietary supplement LifePak on human skin carotenoids measured by Biophotonic Scanner using a non‐invasive Resonance Raman Spectroscopy (RS) technique. We examined skin carotenoids of 88,721 volunteers, and monitored changes in skin carotenoids as a function of life styles and in response to daily consumption of fruits, vegetables, and dietary supplement LifePak. RS skin carotenoids scores are closely, positively correlated with serum carotenoids determined by use of HPLC (r2=0.704, p<0.001). Non‐tobacco users and subjects with less sunlight exposure had significantly higher scores than those for current or former tobacco users or people with high level sunlight exposure (p<0.001). The higher the BMI, the lower the scores (p<0.001), indicating diluted fat‐soluble carotenoids in the body as a function of increased body fat mass. We found that the more daily consumption of fruits‐vegetables and dietary supplements, the higher the scores (p<0.01). Daily LifePak intake increased the RS scores by 24% at Week 4 and by 44% at Week 8 (p<0.001). In conclusion, RS skin carotenoids scores reflect the steady state levels of antioxidant carotenoids in human skin. Fruits‐vegetables intake and LifePak supplementation increase antioxidant capacity in human body, but tobacco use and sunlight exposure reduce it.