Premium
Effects of Exercise in Type 1 Diabetes
Author(s) -
Burrack Adam Lee,
Greany John,
Sewell Diane,
Smith Lisa,
Maher Margaret
Publication year - 2007
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.21.5.a690-d
Subject(s) - medicine , diabetes mellitus , type 2 diabetes , insulin , anthropometry , aerobic exercise , dose , physical therapy , vo2 max , physiology , endocrinology , blood pressure , heart rate
People with diabetes are often encouraged to exercise for benefits such as increased insulin sensitivity and insulin‐independent glucose uptake. However, exercise presents challenges to blood glucose control. Blood glucose control, inflammatory status, and aerobic capacity are interrelated, in ways that are yet unclear. The purpose of this research was to study the subjective and acute effects of exercise on blood glucose control and inflammatory status. Subjects with type 1 diabetes were interviewed extensively about their exercise and medical histories. A subset of these individuals along with controls were recruited to participate in anthropometrics and two exercise sessions, before and after which blood glucose and insulin dosages are recorded and blood samples for measurement of C‐reactive protein levels are collected. The first exercise session is a VO2 max test with short duration, intense effort and the second exercise session is for 30 min at 90% of ventilatory threshold with longer duration, lower intensity. Subject ages are 18–74 yrs, duration of diabetes 8 – 67 yrs, self‐reported typical HbA1c 6.5–8.5%, and range of complications none – multiple. Five of 11 subjects recognize the need for alterations of insulin dosages with exercise and have adjusted accordingly. The further study of blood glucose control and inflammatory marker responses to exercises of varying intensity is in progress.