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Effects of Fe intake during pregnancy on serum concentrations of trace minerals in mothers and neonates
Author(s) -
Kim HyeRa,
Lim HyeonSook
Publication year - 2007
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.21.5.a679
Subject(s) - trace minerals , pregnancy , divalent , serum concentration , medicine , zoology , chemistry , physiology , obstetrics , biology , genetics , organic chemistry
It is a usual practice to recommend taking Fe supplementation during pregnancy. However, there has been some debate on the interference effect of excessive Fe on other divalent trace minerals. In this study, maternal and neonatal serum concentrations of Zn, Cu, Se, Cr, Mn, and Co were assessed according to Fe intakes. A total of 124 pregnant women and their neonates participated. The women consumed 14.1 mg/d of Fe through diets and 72.4 mg/d via supplements for 19.7 weeks, mainly from the 20 th week of pregnancy to delivery. Maternal and neonatal Hb was 11.5 and 14.4 g/dL, respectively. Hb levels both of mothers and neonates were not changed by Fe intake. Serum Fe concentration of mothers and neonates were 148 and 267 μg/dL, respectively. Fe intake did not affect serum concentrations of the minerals examined, including Fe, both in the mothers and neonates. In maternal serum, Fe concentration was related positively to Zn and Se concentration and in neonatal serum, Fe was related positively to Zn, Cu, Mn, Se, and Co. No mineral was found to correlate negatively to Fe concentration both in maternal and neonatal serum. The results of this study indicate that Fe intake during pregnancy, within the usual range of up to 86.5 mg/d, dose not interfere the other divalent trace minerals, including Zn and Cu in mothers and neonates.