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Sensory receptors in periodontal tissue were involved in pressor responses to isometric biting in humans
Author(s) -
Okada Yoshiyuki,
Kamijo Yoshiichiro,
Okazaki Kazunobu,
Masuki Shizue,
Goto Masaki,
Nose Hiroshi
Publication year - 2007
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.21.5.a571
Subject(s) - microneurography , biting , isometric exercise , medicine , baroreflex , heart rate , anesthesia , blood pressure , biology , ecology
We examined whether sensory receptors in periodontal tissue were involved in pressor responses to isometric biting. First, we measured muscle sympathetic nervous activity from the peroneal nerve (MSNA, microneurography), arterial pressures (AP, finometer), heart rate (HR), electromyogram of masseter muscle (EMG), biting force (BF), and finger skin blood flow (FSBF, laser‐Doppler flowmetry) during 2‐min isometric biting at 50% maximal voluntary contraction (MVC) before (No‐Blk) and after pharmacological alveolar nerve block (Blk) in 8 young men. Second, baroreflex gain was determined by the modified Oxford method during biting at 30%MVC (BT) for 5 min and during rest without biting (No‐BT) in Blk and No‐Blk, respectively. In the 1 st study, biting increased AP, HR, and total MSNA (burst amplitude × frequency) and decreased finger cutaneous vascular conductance (FCVC, FSBF/mean AP) in Blk and No‐Blk (P<0.05). However, the changes in AP, total MSNA, and FCVC were markedly less in Blk than in No‐Blk (P<0.05) with no significant differences in EMG and BF between the trials. Second, baroreflex gains in No‐Blk from HR and MSNA responses to pharmacologically altered AP were both lower in BT than in No‐BT (P<0.05), while these significant differences disappeared in Blk. Thus, the sensory receptors in periodontal tissue were involved in increased AP and reduced baroreflex gains during isometric biting.