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Model study of three inspiratory flows upon the alveolar CO2 stratification
Author(s) -
Caucha Luis Jhony,
Cruz Julio C.,
Rueda Luis Antonio
Publication year - 2007
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.21.5.a556-b
Subject(s) - plateau (mathematics) , lung function , tidal volume , fraction (chemistry) , exponential function , flow (mathematics) , mathematics , volume fraction , mechanics , physics , anatomy , mathematical analysis , medicine , thermodynamics , chemistry , respiratory system , lung , organic chemistry
The inspiratory sinusoidal flow of Scherer et al' model ( J. Appl. Physiol . 64 :,1988) is here modified to study its effect upon the alveolar CO 2 fraction as a function of alveolar generation. An exponential function was developed to produce a new flow model (figure 1). A tidal volume of 750 mL was used at 1.5s, 2s and 2.5s time of inspiration. FACO 2 was normalized with the mean inspiratory CO 2 fraction. Results of these models on alveolar CO 2 during inspiration are shown in figure 2 (for clarity only 1.5s and 2.5s are shown). In conclusion, the faster the flow the curve is shifted to the left and the plateau is more diluted. Supported in part by ONG‐Centro de Enseñanza, Investigación y Servicios. 12