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Vinegar ingestion at bedtime appears to moderate waking hyperglycemia in adults with type 2 diabetes
Author(s) -
White Andi,
Johnston Carol S
Publication year - 2007
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.21.5.a49-d
Subject(s) - ingestion , bedtime , postprandial , morning , medicine , type 2 diabetes , meal , crossover study , glycemic , endocrinology , diabetes mellitus , zoology , food science , placebo , chemistry , biology , alternative medicine , pathology
Vinegar ingestion at mealtime reduces the 2‐hour postprandial glycemia by 20–50%. Acetic acid is considered the active component of vinegar and has been demonstrated to reduce disaccharidase activity in cell culture and to raise glucose‐6‐phosphate concentrations in skeletal muscle. This trial examined whether vinegar ingestion at bedtime reduces the next morning fasting glucose (FG) concentration in men and women with type 2 diabetes. Eleven adults volunteered for the trial and recorded FG on three occasions during a single week prior to the initiation of the study. Using a randomized, crossover design with a 3–5 day washout, participants consumed a controlled, standardized diet for two days, and 2 tablespoons of vinegar or water was consumed at bedtime each day with a small snack. FG was recorded the first and third morning at 0700. Meal plans were designed by a registered dietitian to mimic the individual's typical diet; energy was individually adjusted for weight maintenance. Vinegar ingestion did not alter FG significantly (−4%, p=0.098); however, in the six participants who displayed waking hyperglycemia (average pre‐study FG above 130 mg/dL), vinegar ingestion, but not water, reduced FG significantly (−6% or −8 mg/dL; p=0.041). These data suggest that vinegar ingestion may have anti‐glycemic effects apart from mealtime.