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Correlation Between Liver Weight and Dimensions to Patient Demographics
Author(s) -
Alimohammadi Majid
Publication year - 2022
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2022.36.s1.r2981
Subject(s) - demographics , body weight , medicine , correlation , body surface area , hepatocellular carcinoma , weight loss , nuclear medicine , demography , obesity , mathematics , geometry , sociology
Background Treatment of hepatocellular carcinoma (HCC) often involves the use of targeted radiation therapy, chemotherapeutic agents, and percutaneous ethanol injections, but issues of underdosing and overdosing still prevail and dosimetric calculations are often suboptimal. Methods 33 cadavers donated to the University of British Columbia (UBC) Body Donation Program were examined, and data was collected on liver weight and dimensions. The individual’s demographics (height, weight) were obtained from the department’s database, and the liver demographics were correlated with the individuals’ demographics. Results Data was analyzed for correlations between body weight and liver weight, person’s height and the height of the liver along the right surface, body weight and the liver’s length along the superior surface, and body weight and the distance the liver extended left of the midline. A strong positive correlation was identified between body weight and liver weight, with r=0.7475 and p < 0.00001. All other results either concluded weak correlations, or were insignificant. Discussion The strong correlation identified between body weight and liver weight can be used as a potential additional tool during initial clinical examinations to aid dosimetric calculations of radiation and chemotherapy treatments.