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My Theory of the Oxidative‐deoxidative Imbalance in life value
Author(s) -
Wang Yan
Publication year - 2021
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2021.35.s1.00223
Subject(s) - oxidative stress , antioxidant , oxidative phosphorylation , reactive oxygen species , chemistry , biochemistry , microbiology and biotechnology , biology
My Theory about the oxidative‐deoxidative Imbalance in life value has the projects since 1996 till now, which includes the part about the study in nitric oxidativeNO, reactive nitric speciesRNS, Reactive oxygen speciesROS, antioxidant enzymes SOD, NADPH, PRDX and GPXand smaller molecular as GSH, Vitamin C or E; My study had the clinical observation and research part. Current I summarize the whole pathway as the figure presented here. The main theme about the Theory is that the imbalance of the oxidative‐deoxidative state of a special substance happen at it is original prefect balance; the imbalance for RNS/ROS production has the result in interrupt DNA construct, cell, lipids, proteins and other macromolecules function; In biological state, ROS or RNS are generate in natural to take some important roles at cell signaling and homoestasis functional; under oxidative interruption, over products from endogenous and exogeneous pathway which break through the deoxidative defend state to maintain balance of the two sides. Considering of oxidative and antioxidative states imbalance to medical biology in my Theory, currently more important results have published in my articles and books at academic Journals in nations. As usual knowledge, oxidative stress is one of the main reasons to result in degradation to human life span, studying in antioxidant defense system has activated goal to increase life value and qualify. 1 FigureOxidative stress and antioxidant enzymes biology pathway.