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Comparable Blood Velocity Changes in Middle and Posterior Cerebral Arteries During and Following Acute High‐Intensity Exercise in Young Fit Women
Author(s) -
Labrecque Lawrence,
Drapeau Audrey,
Rahimaly Kevan,
Imhoff Sarah,
Billaut François,
Brassard Patrice
Publication year - 2020
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2020.34.s1.08667
Subject(s) - middle cerebral artery , medicine , cerebral autoregulation , cerebral blood flow , transcranial doppler , cardiology , mean arterial pressure , cerebral arteries , blood pressure , intensity (physics) , anesthesia , autoregulation , heart rate , ischemia , physics , quantum mechanics
The influence of high‐intensity exercise training (HIIT) on cerebral blood flow (CBF) regulation remains unclear. HIIT induces surges in mean arterial pressure (MAP), which could be transmitted to the brain, especially early after exercise onset. The aims of this study were to 1) describe regional CBF changes during and following 30 s of high‐intensity exercise and; 2) examine whether dynamic cerebral autoregulation (dCA) is associated with CBF changes. Ten women (age: 26 ± 6 yrs; VO 2max : 48.6 ± 3.8 ml×kg×min −1 ) cycled for 30 s at the workload reached at VO 2max followed by 3 min of passive recovery. dCA was characterized using transfer function analysis of forced oscillations induced by repeated squat‐stands (0.05 and 0.10 Hz). Middle (MCAv mean ) and posterior cerebral artery mean blood velocities (PCAv mean ; transcranial Doppler), MAP (finger photoplethysmography) and end‐tidal carbon dioxide partial pressure (P ET CO 2 ; gaz analyzer) were measured . MCAv mean (+19 ± 10%) and PCAv mean (+21 ± 14%) increased early after exercise onset, returning toward baseline values afterwards. MAP increased throughout exercise (p<0.0001). P ET CO 2 initially decreased by 3 ±2 mmHg (p<0.0001) before returning to baseline values at end‐exercise. During recovery, MCAv mean (+43 ±15%), PCAv mean (+42 ± 15%) and P ET CO 2 (+11 ± 3 mmHg; p<0.0001) increased. TFA gain was higher in the MCA (p < 0.0001). Other dCA metrics were comparable between arteries and unrelated to exercise‐induced cerebral blood velocity changes. In young fit women, blood velocity changes during and following a 30‐s high‐intensity exercise are comparable between MCA and PCA and unrelated to dCA. Support or Funding Information L.L. and S.I. are supported by a doctoral training scholarship from the Fonds de recherche du Québec – Santé (FRQS).