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Modest reductions in face skin temperature do not improve tolerance to a simulated hemorrhagic challenge in exercise heat stressed individuals.
Author(s) -
Tourula Erica,
Lenzini Miramani,
Rhodes Addison,
Hetz Sarah E.,
Pearson James
Publication year - 2020
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2020.34.s1.06331
Subject(s) - heart rate , medicine , blood pressure , forehead , vascular resistance , mean arterial pressure , chin , core (optical fiber) , heat stress , cardiology , anesthesia , surgery , zoology , anatomy , materials science , biology , composite material
Face cooling is associated with autonomic and cardiovascular alterations that accompany an increased blood pressure. Following an exercise heat stress, even minor increases in heart rate and vascular resistance may permit an improved blood pressure control during a simulated hemorrhagic challenge (Lower Body Negative Pressure, LBNP) and improve tolerance. Our aim was to examine whether modest reductions in face skin temperature would improve LBNP tolerance in exercise heat stressed individuals. Ten healthy subjects (Age: 29 ± 13 yrs; Ht: 177 ± 9 cm; Wt: 72.4 ± 8.0 kg) completed two counterbalanced trials (Trial A and Trial B) cycling at 63 ± 6% of their predetermined VO 2 Max whilst wearing a warm water perfused suit and face mask until core temperature had increased 1.5°C. Participants then underwent LBNP to pre syncope. LBNP tolerance was quantified as cumulative stress index (CSI; mmHg*min). Face skin temperature represents the average of forehead, cheek and chin skin temperatures. Face skin temperature was maintained at exercise heat stress values throughout LBNP in Trial A but was reduced via facial fanning in Trial B after 1 minute of LBNP. Arterial blood pressure (MAP, Penaz method), heart rate (HR, ECG), stroke volume (SV, Pulse Contour Analysis) were continuously measured and total peripheral resistance (TPR) was calculated. Following exercise heat stress, core (38.6 ± 0.2 °C), mean skin (38.2 ± 0.6 °C) and face skin (36.4 ± 0.5 °C) temperatures were elevated relative to baseline (all P < 0.05) and not different between trials (all P > 0.05). Face skin temperature remained elevated throughout LBNP in Trial A (36.1 ± 0.5 °C) but was reduced in Trial B (31.3 ± 1.6°C, P = 0.0001 between trials). Following exercise and prior to LBNP, HR was increased (63 ± 8 to 121 ±15 BPM) while MAP (86 ± 7 to 70 ± 6 mmHg) and TPR (12.5 ± 2.0 to 7.7 ± 1.6 mmHg/L/min) were similarly lowered relative to baseline in both trials (all P < 0.05). Mean arterial pressure was similarly reduced at pre syncope in both trials (54 ± 11 and 57 ± 5 mmHg; P < 0.0001 relative to prior to LBNP). TPR and HR increased during LBNP in both trials relative to baseline (both P < 0.05) but were not different between trials 2 minutes after the onset of LBNP (TPR: 7.8 ± 1.7 vs. 7.8 ± 1.8 mmHg/L/min and HR: 131 ± 17 vs. 137 ± 22 BPM, main effect of trial both P > 0.05). CSI was not different between trials (Trial A: 332 ± 176 vs. Trial B: 393 ± 261 mmHg*min; P = 0.482). LBNP tolerance was not improved by face skin cooling in exercise heat stressed individuals. These results suggest that modest reductions in face skin temperature are not accompanied by an improved blood pressure control during a simulated hemorrhagic challenge in exercise heat stressed individuals.