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Synthesis, characterization and antibacterial activity of Co(II) complexes with tricyclic fused chromeno‐pyrimido‐pyrido systems
Author(s) -
Berisha Vjollca,
Koskoviku Mimoza,
Hashani Ismet,
Govori Sevdije
Publication year - 2020
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2020.34.s1.05202
Subject(s) - chemistry , antibacterial activity , antimicrobial , escherichia coli , staphylococcus aureus , tricyclic , metal , proton nmr , stereochemistry , elemental analysis , combinatorial chemistry , medicinal chemistry , bacteria , organic chemistry , biochemistry , biology , genetics , gene
Two novel ligands 7‐iminochromeno[4,3‐d]pyrido[1,2‐a]pyrimidin‐6(7H)‐ones have been prepared. The ligands and their Co(II) metal complexes have been characterized by IR, 13 C‐NMR, 1 H‐NMR, Mass spectra and Elemental analysis. Antimicrobial activities of the ligands and their complexes have been screened against the Escherichia coli ATTC 8739 and Staphylococcus aureus ATTC 25923. The results show that Co (II) complexes possess higher antibacterial activities than ligands towards the bacterial species.