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Whitening Effect of Hydrothermal Extracts of Phragmites Communis and its Active Compound, p ‐coumaric acid
Author(s) -
So Gyeongseop,
Ha Chang Woo,
Jang Sohee,
Kim Sung Hyeok,
Kim Youn Kyu,
Lim Hyosun,
Sohn Eun-Hwa
Publication year - 2020
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2020.34.s1.02061
Subject(s) - tyrosinase , chemistry , dpph , phragmites , hydrothermal circulation , antioxidant , food science , flavonoid , skin whitening , botany , biochemistry , enzyme , biology , pharmacology , ecology , paleontology , wetland , active ingredient
Reed (Phragmites communis) is a perennial grass forming extensive colonies inwetland. The study aimed to compare the antioxidant and whitening effects of roots of P. communis extracts (RPC) by three different extraction processes, using 100% EtOH, 70% EtOH and hydrothermal fluid methods. The amounts of total phenolic compound(TPC), total flavonoid contents(TFC), and p‐coumaric acid (pCA), a major active constituent, were evaluated. Melanogenesis‐related factors such as tyrosinase, L‐DOPA oxidase, and DPPH radical scavenging activities by all three RPC were also measured. Among them, hydrothermal method of RPC(h‐RPC) showed the best effect in the contents of TPC and TFC, DPPH scavenging activity, tyrosinase‐ and L‐DOPA oxidase inhibitory activities. Highest pCA content was also detected from h‐RPC (3.05 ppm). Finally, we confirmed that the color of the cell pellet and the amount of melanin synthesis were significantly reduced in the presence of h‐RPC and pCA in α‐melanin cell stimulating hormoneinduced B16F10 cells. The anti‐melanogenic potential of h‐RPC and pCA will provide an insight into developing a new skin whitening product. Support or Funding Information This research was a part of the project entitled "Development of multi‐functional cosmetic materials derived from halophyte", funded by the Ministry of Oceans and Fisheries, Korea.