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Addressing Craniofacial Anomalies through International Collaborations and Capacity Building
Author(s) -
Butali Azeez
Publication year - 2020
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2020.34.s1.00419
Subject(s) - multidisciplinary approach , identification (biology) , craniofacial , ethnic group , translational research , capacity building , medicine , political science , genetics , pathology , biology , sociology , anthropology , social science , ecology , law
Craniofacial anomalies especially orofacial clefts (OFC) are one of the most common congenital anomalies in Humans. The global prevalence of OFC is 1/700 live births but could be as high as 1/500 in Asians or as low as 0.5/1000 in Africans. These differences in prevalence suggest that there may be different genetic and environmental contributions which requires collective experts across the world for the identification and understanding of genetics, genomics, and environmental factors as well as the interplay between these factors. International collaborations literally mean multi‐ethnic research to identify the causes, risk factors and opportunities for prevention of OFC by collecting data and samples from individuals around the world. The clinical ‐basic‐translational research required for OFC means requisite experts around the world, which then means training and capacity building. In this talk, the audience will have the opportunity to listen to how international collaborations around OFC is driving new discoveries and capacity building in Africa. Additional information on how multidisciplinary expertise in clinical medicine/dentistry, human genetics, developmental biology, anthropology, epidemiology, bioinformatics and implementation science is setting the stage for prevention of OFC will also be shared. Support or Funding Information DE022378 and Robert Wood Johnson Foundation Grant number 72429