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Effect of Resistance Exercise on Bones in Calcium‐deficient Rats
Author(s) -
Hirakawa Tomoe,
Fujii Takako,
Matsumoto Kinuyo,
Okamura Koji
Publication year - 2019
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2019.33.1_supplement.lb553
Subject(s) - calcium , medicine , endocrinology , femur , calcium metabolism , chemistry , surgery
Resistance exercise has been reported to enhance the reuse of iron in the body (Fujii T et al. Biol Trace Elem Res. 2014). Exercise increases the calcium absorption rate and bone mass. However, aerobic exercise reportedly does not lead to any improvements in bone strength in calcium‐deficient rats (Senge et al. J Physiol Soc Japan. 2003), although the effects of resistance exercise on bone in these animals are unclear. Therefore, we investigated the effect of resistance exercise on bones in calcium‐deficient rats. Twenty‐one male Sprague‐Dawley rats (4 weeks old) were divided into a calcium‐sufficient diet group (5 g calcium/kg diet) and a calcium‐deficient diet group (1.67 g calcium/kg diet), and half of the rats in both groups were subjected to climbing exercise training (5 minutes × 6 sets, 5 minutes of rest between sets) every other day for 3 days a week. The rats were euthanized after four weeks of the treatment. There were no significant differences in the blood calcium concentration among the four groups. The body weight and the weight of the flexor hallucis longus muscle, soleus muscle and kidneys were significantly higher in the exercise groups than in the non‐exercise groups, while no significant differences in these values were found between the calcium‐sufficient and calcium‐deficient diet groups. The weight, center width, rupture strength and stiffness of the femur were significantly higher in the calcium‐sufficient group than in the calcium‐deficient group, whereas no significant effect of exercise was observed. Resistance exercise enlarged the skeletal muscle in calcium‐deficient rats; however, this form of exercise showed no marked effect on bone parameters. This abstract is from the Experimental Biology 2019 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .