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Preliminary Definitions for Sacroiliac Joint Pathologies in the OMERACT Juvenile Idiopathic Arthritis MRI Score (OMERACT JAMRIS‐SIJ)
Author(s) -
Otobo Tarimobo Michael,
Tolend Mirkamal,
Maksymowych Walter P,
Conaghan Philip G,
Heijd Desiree,
Weiss Pamela,
SudolSzopinska Iwona,
Herregods Nele,
Jaremko Jacob L,
Jans Lennart,
Meyer Arthur B,
Rumsey Dax Rumsey,
Inarejos Emilio C,
Kirkhus Eva,
Thorpe Kevin,
Rossum Marion A J,
Perez Manuela,
Tzaribachev Nikolay,
Sandhya Pulukool,
Tse Shirley,
Simone Appenzeller,
Swami Vimarsha G,
Touma Zahi,
Lambert Robert G,
Doria Andrea S
Publication year - 2019
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2019.33.1_supplement.453.8
Subject(s) - medicine , physical therapy , magnetic resonance imaging , sacroiliac joint , arthritis , radiology
Purpose Clinical assessment of the Sacroiliac Joint (SIJ) has limitations due to the location and anatomy of the joint. Magnetic Resonance Imaging is a sensitive, non‐invasive tool in detecting early SIJ inflammatory changes and structural damage in Juvenile Idiopathic Arthritis (JIA). The quantification of interval change of pediatric SIJs using an MRI based scoring methods will serve as an important objective outcome measure for the assessment disease severity and treatment effectiveness in JIA. Methods The OMERACT consensus‐driven methodology consisting of iterative surveys and focus group meetings within an international group of pediatric rheumatologists and radiologist was utilized to decide the measurement construct, items, and definitions. Consensus was deemed to have been achieved if greater than 70% agreement was reached among voting attendees at the session in the absence of greater than 15% present or more in strong disagreement. Results Twenty‐eight international multidisciplinary experts from North America, Europe, South Asia, and South America participated in the study. Two domains, inflammation and structural, were identified. Definitions for bone marrow edema, joint space inflammation, capsulitis, and enthesitis were derived for joint inflammation; sclerosis, erosion, fatty lesion and ankylosis were defined for assessing structural joint changes. Conclusion Preliminary consensus‐driven definitions for inflammation and structural elements have been derived, underpinning the ongoing development of the Juvenile arthritis SIJ MRI scoring system (JAMRIS‐SIJ). Support or Funding Information Hospital for SickKids Research Trainee Fund (RESTRACOMP) This abstract is from the Experimental Biology 2019 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .