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Blunted Blood Pressure to Hand Grip Exercise in Individuals with Intellectual Disabilities: Preliminary Results
Author(s) -
Hilgenkamp Thessa,
Schroeder Elizabeth C.,
White Daniel W.,
Baynard Tracy,
Fernhall Bo
Publication year - 2018
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2018.32.1_supplement.891.8
Subject(s) - isometric exercise , blood pressure , pulse pressure , medicine , heart rate , hemodynamics , photoplethysmogram , cardiology , diastole , population , physical therapy , physical medicine and rehabilitation , psychology , environmental health , filter (signal processing) , computer science , computer vision
Individuals with intellectual disabilities (ID) have limited work capacity. In individuals with Down syndrome, this has been previously linked to autonomic dysfunction. Previous research suggests autonomic dysfunction and altered hemodynamics may also be present in individuals with ID without Down syndrome but this has not been tested. PURPOSE To compare the autonomic and hemodynamic response to isometric handgrip (HG) exercise in individuals with ID to a control group without ID. METHODS Nine individuals with ID and 19 individuals without ID had heart rate and blood pressure continuously recorded via an ECG‐lead and finger‐photoplethysmography in the seated position. Isometric HG was performed at 30% of maximal voluntary contraction for 2 min. Recordings were acquired for the last 2 min of quiet rest, HG, and the first 2 min of recovery. RESULTS Individuals with ID showed smaller increases compared to individuals without ID for systolic and diastolic blood pressure, mean arterial pressure and pulse pressure during HG (p<0.001; Table). CONCLUSION Despite no HRV differences, these preliminary results suggest a blunted blood pressure response to isometric HG in individuals with ID, which may help explain low fitness levels observed in this population. Support or Funding Information The research leading to these results has received funding from the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007–2013) under REA grant agreement no 625455. This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .