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AFTER EFFECTS OF A SINGLE BOAT OF AEROBIC EXERCISE IN THE HEMODYNAMIC AND AUTONOMIC VARIABLES IN STAGE 3 CHRONIC KIDNEY DISEASE PATIENTS
Author(s) -
Rezende Rafael Andrade,
Pinto Walter Pereira,
Dalboni Maria Aparecida,
Tinucci Tais
Publication year - 2018
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2018.32.1_supplement.855.4
Subject(s) - medicine , blood pressure , aerobic exercise , cardiology , heart rate , diastole , kidney disease , coronary artery disease , physical therapy
The prevalence of chronic kidney disease (CKD) has increased exponentially in recent years mostly due to hypertension and diabetes. Effective treatment of these diseases is important in slowing the progression of CKD. An important tool to improve blood pressure (BP) control is physical exercise. Physical training consistently decreases the BP of hypertensive individuals. In addition, it is known that physical training improves cardiac autonomic modulation efficiently. Acute physical exercise promotes post‐exercise hypotension (PEH) and improves cardiac autonomic modulation. Thus the aim of the study was to evaluate the effect of an acute session of aerobic exercise on blood pressure and on the autonomic cardiac modulation of stage 3 CKD patients. Methods 16 volunteers, being 8 CKD, 53 ± 7 years; creatinine clearance 49 ± 9 ml/min; Systolic BP 127 ± 6 mmHg; Diastolic BP 79 ± 8 mmHg) and 8 controls (CON), 50 ± 7 years; Systolic BP: 112 ± 10 mmHg; Diastolic BP 75 ± 5 mmHg, performed 2 experimental sessions. An aerobic exercise session on cycle ergometer, 45 minutes at 50% VO2peak and a 45‐minute session at rest. The sessions were held at random. The auscultatory measurements of BP and heart rate (HR) measurements by palpation of the radial artery were performed before and after the interventions. Descriptive data analysis (mean and standard deviation), two‐factor ANOVA (group × moment), and calculation of the actual effect of exercise [(Δ exercise) − (Δ control)] were performed with P <0.05. Results Exercise decreased systolic BP (CKD −13 ± 3 and CON −7 ± 2), diastolic BP (−9 ± 4 and 3 ± 1) and increased HR (3 ± 2 and 8 ± 8). In cardiac autonomic modulation there was no significant difference between the two groups. Discussion and Conclusions Patients with CKD have a higher mean systolic BP decrease and a lower HR increase after an acute aerobic exercise session when compared with healthy subjects. No differences were observed in diastolic BP, mean BP and cardiac autonomic modulation This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .