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Dengue Fever: the Next Global Killer
Author(s) -
Raynes Edilberto A.,
Glymph Kelly,
Coker Karen,
Agazuma Keshia,
Michaels Natalie,
Menchavez Melinda Roca,
Raynes Janika Ziarah Rellama
Publication year - 2018
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2018.32.1_supplement.819.17
Subject(s) - dengue fever , dengue virus , outreach , public health , vector (molecular biology) , environmental health , virology , medicine , biology , political science , biochemistry , nursing , gene , law , recombinant dna
The purpose of the study is to review the epidemiological aspects of the dengue fever infection. The infection is caused by dengue viruses (DENV), which have four different serotypes and antigenically distinct. The DENV is transmitted by a vectorborne day biting mosquito, Aedes agypti . The clinical spectrum ranges from dengue fever to dengue hemorrhagic fever. Based on our review from the World Health Organization, Centers for Diseases Control and Prevention, as well as from other studies, the disease is still more endemic in the Southeast Asia and Western Pacific regions with an estimate of 300 million infections annually, mostly affecting children. Factors that contribute to the emergence of DENV infection worldwide include substandard living conditions, virus evolution, lack of vector control programs, and international travelers. The best measure of DENV control is prevention by increasing awareness of the public through coordinated outreach programs to the community coordinated by various stakeholders. There are still no available vaccines and specific medications to cure. A multidisciplinary collaboration needs to be mobilized to combat the vector. Support or Funding Information None This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .