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Influence of Sex and Exercise Intensity on Acute Flow‐Mediated Dilation Response to Aerobic Exercise in Healthy Young Adults
Author(s) -
Kim HanKyul,
Hwang ChuehLung,
Lim Jisok,
Yoo JeungKi,
Perez Hannah,
Handberg Eileen M.,
Christou Demetra
Publication year - 2018
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2018.32.1_supplement.587.6
Subject(s) - medicine , brachial artery , reactive hyperemia , aerobic exercise , cardiology , heart rate , crossover study , intensity (physics) , interval training , physical therapy , blood pressure , blood flow , physics , alternative medicine , pathology , quantum mechanics , placebo
Brachial artery flow‐mediated dilation (FMD), a measure of endothelial function, is an independent predictor of future cardiovascular events. Sex and exercise intensity influence the acute FMD response to aerobic exercise in older adults, but in young adults this has not been investigated. Therefore, the purpose of this study was to compare the acute FMD response to a single bout of high‐intensity interval training (HIIT), moderate‐intensity continuous training (MICT) and low‐intensity continuous training (LICT) in young men vs. women. Twenty‐eight healthy young adults (14 men and 14 premenopausal women, 21.2±0.3 vs. 21.5±0.8 years of age, means ± SE, P =0.7) participated in this randomized crossover study. Brachial artery FMD was measured in response to reactive hyperemia following 5‐min forearm occlusion using high resolution ultrasonography. FMD measures were obtained prior to exercise, at the end of a single bout of HIIT (40 min, 4 × 4‐min intervals at 90% peak heart rate (HR peak ), MICT (47 min, 70% HR peak ) and LICT (47 min, 50% HR peak ) on the treadmill and following 60‐min recovery from exercise. The acute FMD response was influenced by exercise intensity but not sex (P=0.006 for exercise intensity × time and P=0.9 for sex × exercise intensity × time), thus the results are presented for men and women combined. FMD was attenuated by 20.7% following the end of HIIT (6.96±0.51 vs. 5.47±0.48%, pre‐ vs. end of exercise; P=0.001) and returned to pre‐exercise levels following 60‐min recovery (P>0.99). However, FMD did not change in response to MICT(7.10±0.53 vs. 6.32±0.57 vs. 7.26±0.37%; P≥0.3) and LICT (7.14±0.41 vs. 7.46±0.56 vs. 7.15±0.43%; P>0.99). In conclusion, exercise intensity, but not sex, significantly impacts the acute FMD response to aerobic exercise in young adults. This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .