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Discovery and Engineering of Plant Chemistry for Plant and Human Health
Author(s) -
Sattely Elizabeth
Publication year - 2018
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.2018.32.1_supplement.380.3
Subject(s) - plant biology , limiting , synthetic biology , arabidopsis , metabolic engineering , plant science , plant metabolism , computational biology , human health , plant growth , transformative learning , plant species , biochemical engineering , biology , engineering , botany , biochemistry , gene , mechanical engineering , psychology , rna , pedagogy , mutant , medicine , environmental health
Plants are some of the best chemists on the planet and produce an impressive array of small molecules. We are inspired by the fact that humans have become extraordinarily reliant on plant‐derived molecules for food, medicine, and energy. However, remarkably little is known about how plants make these molecules, limiting our ability to engineer and optimize plant metabolic pathways. New plant genome sequences and synthetic biology tools have opened the door to three transformative research areas under investigation in my lab: 1) Identifying the minimum set of enzymes required to make known plant‐derived molecules and non‐natural derivatives through metabolic engineering, and 2) discovering new molecules from plants, and 3) developing new strategies to enhance plant fitness. In this talk, I will describe some of our recent efforts to accelerate the discovery of complete plant pathways for known and novel molecules, not only in the model plant Arabidopsis but also in non‐model plants. This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .