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Characteristics of insulin resistance in Korean Type 2 DM Patients
Author(s) -
Yu So Young,
Hong Hye Sook,
Huh Kap Bum,
Park Jee Won,
Kim Wha Young
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.5.lb96-b
Subject(s) - insulin resistance , medicine , triglyceride , waist , endocrinology , body mass index , insulin , abdominal obesity , type 2 diabetes , diabetes mellitus , cholesterol
The purpose of this study is to investigate the association of insulin resistance with anthropometric variables, dietary intakes, blood profiles in Korean type 2 DM patients. The subjects were 175 patients visited DM clinic, and they were classified into 3 insulin resistance groups based on K ITT index: group A, K ITT < 1; group B, 1≤ K ITT >3; group C, 3 ≤ K ITT . The most severe insulin resistant group (group A) showed significantly higher waist circumference and percent abdominal fat, and higher fasting blood values of glucose, triglyceride, C‐peptide, insulin, and C‐reactive protein, compared to groups B and C. Partial correlation analysis, corrected for duration of diabetes, revealed that K ITT index was negatively correlated with BMI, waist circumference, percent body fat, percent abdominal fat, fasting glucose, triglyceride, C‐peptide, and insulin. The subjects with insulin resistance seemed to have lower intakes of vitamin A, folic acid, and zinc; the higher proportion of subjects in group A consumed vitamin A, folic acid, and zinc insufficiently (< 75% KRDA) than in group B.