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Reduction in abdominal visceral fat improves endothelium‐dependent dilation in overweight and obese humans
Author(s) -
Benay Francoise Judith,
Achen Kara,
Lawson Brooke,
Seals Douglas,
Beske Stacy
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.5.lb17
Subject(s) - medicine , overweight , brachial artery , weight loss , visceral fat , obesity , cardiology , abdominal fat , diabetes mellitus , endocrinology , urology , blood pressure , insulin resistance
Elevated abdominal fat is associated with vascular endothelial dysfunction, increasing the risk for atherosclerosis. We hypothesized that energy restriction‐mediated weight loss would improve endothelial dependent dilation (EDD) and that this improvement in EDD would be most closely related to reductions in abdominal visceral fat (AVF, computed tomography). Brachial artery flow‐mediated dilation (FMD %, duplex ultrasound) was measured before and after 12‐weeks of energy restriction in sedentary, normotensive, non‐diabetic overweight and obese (25