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Aerobic performance is related to restraint tolerance in rats
Author(s) -
Balthazar Cláudio Heitor,
Coimbra Cândido Celso
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.5.a1471-b
Subject(s) - oxygen , vo2 max , zoology , treadmill , basal (medicine) , chemistry , aerobic exercise , endocrinology , medicine , biology , heart rate , organic chemistry , blood pressure , insulin
The aim of this study was to compare the metabolic cost of restraint stress (RS) with oxygen consumption during progressive exercise (PE) until attain VO 2 max in rats. Male rats wistar (180–220 g), where housed under controlled conditions. The rats were submitted to PE protocol on a motor‐driven treadmill (starting speed of 10 m.min −1 ; increasing 1 m.min −1 each 3 min step; 15% inclination; until attain VO 2 max). VO 2 max was determined by failure of the rats to continue running. Two days after the PE, the rats were submitted to RS protocol (30 min of restraint), with the use of a plastic tube (21 cm long and 4.5 cm in diameter) specially designed to restraint the rats. The oxygen consumption was recorded during the two protocols. The oxygen consumption recorded 30 min before the PE starts was determined as the basal consumption. Data are reported as means ± SEM of 7 rats: Basal: 19.7 ± 1.6 ml.Kg −1 .min −1 ; RS: 31.3 ± 1.1 ml.Kg −1 .min −1 ; VO 2 max: 53.7 ± 3.8 ml.Kg −1 .min −1 . Our data showed that RS induces an oxygen consumption similar to a medium‐intensity exercise, equivalent to 50% that the observed at VO 2 max. We had also observed a strong correlation between the VO 2 max and lower metabolic cost during restraint stress (r 2 =0.9123, p<0.02). Our results indicate that best aerobic performance rats are more tolerant to RS. Supported by: CNPq; FAPEMIG.