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Carbohydrate metabolism during period of different diet types
Author(s) -
AbdulRahman Alya'a A,
Afifi Nahla,
AlNaemi Hamda
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.5.a1466-b
Subject(s) - carbohydrate , obesity , medicine , carbohydrate metabolism , endocrinology , weight gain , metabolism , insulin , zoology , pellets , body weight , chemistry , biology , paleontology
Obesity became a great epidemic disease all over the world, and loosing weight is a high priority concern of most obese individuals. A low carbohydrates and a high protein diets became a popular solutions for obese people therefore, the goal of this study was to evaluate the effect of a high protein diet on body weight and glucose metabolism. Adult male Spargue‐Dawely rats (300–400g) were divided into three groups; group 1, fed on standard chow pellets, group 2 fed on 75% high carbohydrates diet and 25% chow pellets, and group 3 fed on 75% high protein diet and 25% chow pellets for two weeks. Body weight, food and water intake were recorded all through the experiment. Fasting glucose and insulin values were measured using biochemical and Elisa analysis, respectively. Results showed that after two weeks there was a significant increase (P<0.05) in body weight gain in group 2 (35.20±13.17), and a significant decrease (P<0.05) in B. Wt. gain in group 3 (11.25±4.21) compared to B. Wt. gain of the control group (28.80±1.72). Food intake was increased significantly in both groups 2 & 3, whereas there was no significant difference in water intake between all groups. Fasting glucose level was increased significantly in both the high carbohydrate group (8.98±1.79), and the high protein group (9.58±1.04) compared to the control value (5.97 ± 1.00), whereas no significant differences in insulin level was detected between all groups. In conclusion consumption of a high protein diet for a short period of time caused a significant weight loss and a rise in blood glucose level that might be produced by de novo process.