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Type 2 Diabetes–Lessons Learned From Clinical Studies
Author(s) -
Petersen Kitt
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.5.a1307-c
In this lecture I will review the application of Magnetic Resonance (MR) techniques to examine the pathogenesis of insulin resistance and type 2 diabetes in humans: Basic Principles of NMR Spectroscopy 13 C NMR studies to examine the regulation of muscle glycogen synthesis in normal and type 2 diabetic patients 31 P NMR studies to examine the rate controlling step of Insulin Stimulated Muscle Glycogen Synthesis in normal and type 2 diabetic patients The mechanism of insulin resistance in lipodystrophy The mechanism of insulin resistance in aging The mechanism of insulin resistance in Offspring of diabetic parents The effect of weight loss on hepatic steatosis, hepatic insulin resistance and hyperglycemia in patients with type 2 diabetes