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RESPONSES OF BODY COMPOSITION AND MINERAL CONTENT RELATED TO MATERNAL NUTRITIONAL STATUS
Author(s) -
Ferreira Andrea,
Suarez Cristina,
Rodríguez Patricia,
Zeni Susana,
Friedman Silvia
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.5.a1065-a
Subject(s) - weanling , leptin , lactation , endocrinology , medicine , bone mineral content , composition (language) , calorie , chemistry , zoology , bone mineral , biology , pregnancy , obesity , osteoporosis , linguistics , philosophy , genetics
Preceding studies have shown a strong correlation between maternal nutritional status as an important predictor of morbidity in mothers and pups. In order to assess the effect of long term eucaloric diets, with different carbohydrate to fat (CH:F) calorie ratio with either adequate (0.6%) or low (0.3%) calcium content on body composition and bone mineral content, thirty rats were evaluated at the end of the lactation period. At weanling, female Wistar rats were randomly assigned one of the following diets: a) CH: F = 1:1; 0.6%; b) 3:1 0,6 % and c) 3:1 0,3%. At day=70, rats were mated and at weanling mothers (M) and pups (P) were studied. Body weights (BW), bone mineral content (BMC) by DEXA Lunar, percentage of body fat (% BF) by chemical method (AOAC) and serum leptin (ELISAng/ml) were measured. Results are expressed as mean ± SD:Dietary fat restriction produced a decreased in BF in all groups, being significant in pups. BMC was reduced in mothers eating low Ca diet. Leptin levels remained unchanged. In pups, the decreased in BF content did not correlate with serum leptin levels; taken together, these findings suggest that leptin may act improving lipid tissue development and involved in body mineral content. Awarded by UBACyT O 004.