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Anemia during pregnancy: associated factors, and maternal and perinatal outcomes
Author(s) -
Ahluwalia Namanjeet,
Parant Olivier,
Baron Mireille,
Grandjean Helene
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.5.a1049-a
Subject(s) - medicine , pregnancy , anemia , odds ratio , obstetrics , logistic regression , prenatal care , risk factor , retrospective cohort study , pediatrics , medical record , population , genetics , biology , environmental health
We examined the factors associated with anemia during pregnancy (AnP) as well as the association of AnP with several maternal and neonatal outcomes in a retrospective cohort of women who had received prenatal care in the University hospital (CHU) in Toulouse (1994‐2000). Computerized medical information was retrieved for 19,925 women; complete data on maternal characteristics, and maternal and perinatal outcomes were available on 16,968 women (age: 30±5 y). The prevalence of moderate anemia (hemoglobin < 10 g/dL) was 6.1%. Age (<18 y), lower level of education, multiparity, African or Asian origin, and infections were associated with AnP; odds ratio (OR) for these risk factors ranged between 1.3 (for infections) to 6.1 (African origin). Using multiple logistic regression, after accounting for maternal age, marital situation, parity, smoking, prepregnancy BMI, ethnicity, and infections during pregnancy, AnP remained independent risk factor for premature birth, cesarean delivery, hemorrhagic delivery, and infections in the newborn in the first week of life; OR (95% CI) were 1.6 (1.4‐2.0), 1.5 (1.3–1.8), 1.5 (1.3–1.9), and 1.2 (1.01–1.4), respectively. These findings suggest that anemia in pregnant women is an independent and important risk factor for poor maternal and neonatal outcomes. Its prevention prior to pregnancy is therefore of ultimate public health importance.