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Influence of overweight and obesity on the predictive value of selected nutritional index as predictors of surgical complications
Author(s) -
Zago Liliana B.,
Dupraz Hernán,
Gasali Fernando,
Río María Esther
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.5.a1033-a
Subject(s) - overweight , medicine , obesity , creatinine , gastroenterology , body mass index , incidence (geometry) , endocrinology , physics , optics
In a previous work we had been selected biochemical index of nutritional status with high predictive value (PV) of surgical complications (Experimental Biology 2004): urea nitrogen/creatinine ratio (UN/C; PV=78%), transthyretin (TTR; PV= 65%), fibronectin (FN; PV= 65%), plasma vitamin A (VA; PV= 72%), and erythrocyte protoporphyrin (EP; PV= 78%) showed significant association between deficiency values and postoperative complications (C) of hernia and lithiasis surgical procedures. Patients (n= 100) showed a trend to overweight and obesity: 29% of normal weight (N; BMI 18.5–24.9), 56% overweight (OW; BMI 25–29.9) and 15% obese (O; BMI 3 30). Incidence of C increased with weight: 17.2% in N, 28.6% in OW and 33.3% in O, although differences among groups were n.s. (p= 0.4131). In this work, influence of OW and O on PV of above markers was studied. PV (Success/Total predictions) of markers in patients grouped in 2 categories of BMI: N and (OW + O) was analyzed. Results indicated that presence of OW or O decrease the PV of UN/C and VA from 90% and 83% in N, to 73% and 67% respectively, in (OW + O), not affecting the other markers. We conclude that overweight and obesity should be taken into account as confusion factors of PV of markers. Supported by UBACyT B077