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Effects of dairy calcium on lipid profile in overweight/obese postmenopausal women
Author(s) -
Fakhrawi Dina H,
CorderoMacIntyre Zaida,
Beesan Lawrence,
Feleke Daniel,
Kim Hannah,
Darnell Allan,
Fernandez MariaLuz
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.5.a1024-c
Subject(s) - medicine , endocrinology , overweight , leptin , lipid profile , insulin , calcium , cholesterol , obesity , chemistry
We evaluated the effects of low (LC, ~800 mg/d) and high (HC, ~1400 mg/d) dairy calcium on body weight, plasma lipid profile, glucose, insulin and leptin in overweight/obese postmenopausal women (n = 56) with a BMI 33.1±5.7kg/m 2 . The 3‐month weight loss program involved calorie restriction (1,400 kcal) and macronutrient intake of 51% carbohydrates, 20.7 % proteins and 27.6 % fat. Three randomly selected days of diary intake indicated that all participants were taking an average of 832 mg/day at baseline. At 3 months the LC group had an average intake of 861 ± 721 mg while the intake of the HC group was 1340 ± 494 mg (P < 0.05). Since there were no differences in any of the measured parameters between groups, except for plasma glucose, pooled data of the 56 women were analyzed. Plasma glucose decreased from 74.7 ± 31.9 to 71.1 ± 12.2 mg/dL (P < 0.05) in the HC group only. After 3 months, there was a significant decrease (P <0.0001) for all participant in LDL cholesterol from 116.5 ± 46.5 to 98.4 ± 36.6 mg/dL while HDL cholesterol was raised from 60.0 ± 15.7 to 63.8 ± 12.2 mg/dL (P < 0.05) following the intervention. Plasma triglycerides and insulin were not affected by this intervention while plasma leptin decreased from 30.2 ± 10.1 to 28.3 ± 10.7 μg/L (P < 0.05). We conclude from this study that caloric restriction with dairy calcium efficiently improved lipid profiles and leptin concentration in this population.